Impact Funding Resources
Enabling and supporting researchers in developing and deploying advanced human-specific cell models for research and testing.
The Physicians Committee for Responsible Medicine, a nonprofit that advances human-based science, and InSphero, a global leader in 3D in vitro technology for drug safety and efficacy testing, are pleased to offer the 2025 Human Advanced In Vitro Model Initiative (HUMAIN) Award. The HUMAIN Award recognizes researchers working to expand access to and accelerate the uptake of human-specific nonanimal approaches.
The Physicians Committee for Responsible Medicine, a nonprofit that advances human-based science, and InSphero, a global leader in 3D in vitro technology for drug safety and efficacy testing, are pleased to offer the 2025 Human Advanced In Vitro Model Initiative (HUMAIN) Award. The HUMAIN Award recognizes researchers working to expand access to and accelerate the uptake of human-specific nonanimal approaches.
End Date14 Jul 2025 Funding AmountUSD 20k (in technology credits) Funding Resource TypeAward
Funding ProviderPhysicians Committee for Responsible Medicine (PCRM),InSphero
Award
Physicians Committee for Responsible Medicine (PCRM),InSphero
The Physicians Committee for Responsible Medicine, a nonprofit that advances human-based science, and InSphero, a global leader in 3D in vitro technology for drug safety and efficacy testing, are pleased to offer the 2025 Human Advanced In Vitro Model Initiative (HUMAIN) Award. The HUMAIN Award recognizes researchers working to expand access to and accelerate the uptake of human-specific nonanimal approaches.
Five winning laboratories will receive:
• $20,000 toward InSphero technology (Akura™ Spheroid Microplates, Akura™ Organ-on-Chip Technology, 3D InSight™ Microtissues, ARCTis™ Cryo Microtissues) or services (3D InSight™ Services)
• Access to an inaugural one-day training course in Schlieren, Switzerland, with up to $1,000 in travel grants to attend
• Two hours of monthly consulting with InSphero experts
• Up to $2,000 in travel grants to present findings at scientific conferences
• $2,500 towards open access publication fees
Eligibility:
• Nonprofit, educational, and/or research institutions (U.S. or non-U.S.)
• Projects should utilize human-specific, nonanimal approaches
Proposals will be reviewed based on the following criteria:
1. Novelty
Proposals should present a novel approach, concept, or methodology that advances scientific knowledge or technological innovation. Clearly explain how the project differs from existing solutions and what unique contribution it makes to the field. Highlight any breakthrough potential or innovative aspects of the research.
2. Completeness and Scientific Rigor
Ensure the proposal is well-structured, logically developed, and based on sound scientific principles. Clearly define the research objectives, hypotheses, and methodology.
3. Complementarity to Existing Solutions
Describe how the project fits into the broader scientific landscape and complements existing solutions rather than duplicating them. Identify any gaps in current methodologies or technologies that the research addresses and explain how the approach integrates with or enhances existing knowledge and applications.
4. Feasibility, Chances vs. Risks
Consider the feasibility of the project by assessing the stated objectives, required resources, and potential challenges. Proposals should demonstrate a clear understanding of the balance between potential breakthroughs and associated risks, ensuring a practical and achievable research plan. A risk-benefit analysis is NOT required for this application.
5. Impact on 3Rs (Replacement, Reduction, and Refinement)
Projects should align with the principles of the 3Rs, particularly in the context of replacing animal testing. Proposals must include a well-informed estimate of the number of animals that will be replaced by this project, specifying the species and types of animal tests involved.
6. Relation to InSphero Offers
The HUMAIN initiative funds researchers to utilize InSphero's technology and services. Proposals with study designs that can be achieved with InSphero’s offerings will be given preference.
